A new antibiotic victomycin (XK 49-1-B-2). II. Isolation, purification and physicochemical and biological properties.
نویسندگان
چکیده
A new antibiotic, victomycin, is active against a variety of Gram-positive and Gram-negative bacteria, and also has in vivo activity against solid Sarcoma 180 and Ehrlich ascites carcinoma. It belongs to the phleomycin-bleomycin group of antibiotics and has been differentiated from all known phleomycins and bleomycins by its physicochemical properties and thin-layer chromatograms.
منابع مشابه
The antibiotic YA-56 complex: isolation, purification and physicochemical properties of the main components.
Isolation, purification and physicochemical properties of the antibiotic complex YA-56, a family of phleomycin-bleomycin group, are described. The antibiotic YA-56 complex was found to be composed mainly of two active components named YA-56X and Y. These components were clearly differentiated from the reported phleomycins and bleomycins by their physicochemical properties. However, by direct co...
متن کاملFredericamycin A, a new antitumor antibiotic. I. Production, isolation and physicochemical properties.
A new antitumor antibiotic, fredericamycin A (FCRC-A48, NSC-305263), has been isolated from a strain of Streptomyces griseus (FCRC-48). Based on its unique ultraviolet-visible spectrum, infrared spectrum, proton and carbon-13 nuclear magnetic resonance spectra and mass spectra, it is judged to be a novel acid-base indicator type of compound. Its production, isolation and physicochemical propert...
متن کاملIsolation, purification and biological properties of horse precipitating and non precipitating antibodies.
--Non-precipitating antibodies localized in the IgG,, IgGb and IgGc were isolated from serum of horses inoculated with DNP-HGG, with or without anti-DNP precipitins. The methods for isolation and purification of precipitating and non precipitating antibodies are described. The physicochemical characteristics and biological properties of precipitating and non-precipitating antibodies localized i...
متن کاملPREPARATION OF HIGHLY PURIFIED SOLVENTDETERGENT COA GULATION FACTOR VII AND FACTOR IX CONCENTRATES FROM PROTHROMBIN COMPLEX (PPSB)
In this study, anion-exchange chromatography was used to purify factor VII and factor IX from prothrombin complex (PPSB), which contains coagulation factors II, VII, IX and X. For this purpose, DEAE-Sepharose CL-6B gel , Pharmacia column XK-26 , high flow rate and two stepwise gradients with phosphate citrate buffer were used. The yield of the two lyophylized products, factor VII and factor...
متن کاملProteins Separation and Purification Methods with Focus on Chromatography: a Review Study
Before describing the structure and mechanism of action of a protein, it must first be subject to purification procedure. Protein purification is a set of processes in which one or a small number of proteins are purified from a complex compound that may be a complete cell, tissue, or organism. Understanding the functions, structural properties, and interactions of the protein are directly re...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 28 5 شماره
صفحات -
تاریخ انتشار 1975